| Test Name: | Cyclosporine |
| Epic Order Code: | LAB874 |
| CPT Code: | 80158 | | |
| Specimen(s) Type: | Whole Blood; Full tube required. |
| Acceptable Container(s): |  Top is purple (lavender). |
| Testing Schedule: | Tested as received between the hours of 7 a.m.-3 p.m.; 7 days/week |
| Turn Around Time: | STAT: NA |
| | Routine: 2 hours when received between 7 a.m.-3 p.m.; Specimens received after 3 p.m. are held until the following morning. |
| Collection Information: | No special patient preparation is required. Obtain specimen by standard collection procedures. |
| Transport Information: | Deliver to lab immediately. All specimens must be signed into the laboratory. |
| Reference Clients: | If unable to deliver to the lab within 1 hour, store and transport at 2-8° C. Do not centrifuge. Specimen must be received in the lab within 7 days. If longer storage is required, store and transport the specimen at -20° C for up to 30 days. |
| Causes for Rejection: | Improperly labeled, incorrect container, contaminated, insufficient quantity, incorrect/delay in transport. |
| Reference Range: | Therapeutic: 100 - 400 ng/mL |
| | Potentially toxic: > 600 ng/mL |
| Additional Information: | When elimination of cyclosporine is impaired, i.e., during cholestasis, cyclosporine metabolites may accumulate, and cyclosporine concentration may be overestimated. |